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Protective Effects of Polydatin on Septic Lung Injury in Mice via Upregulation of HO-1

The present study was carried out to investigate the effects and mechanisms of polydatin (PD) in septic mice. The model of cecal ligation and puncture (CLP-)induced sepsis was employed. Pretreatment of mice with PD (15, 45, and 100 mg/kg) dose-dependently reduced sepsis-induced mortality and lung in...

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Detalhes bibliográficos
Main Authors: Xiao-hui Li, Xia Gong, Li Zhang, Rong Jiang, Hong-zhong Li, Meng-jiao Wu, Jing-yuan Wan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2013-01-01
Colecção:Mediators of Inflammation
Acesso em linha:http://dx.doi.org/10.1155/2013/354087
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