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Interleukin-21 accelerates thymic recovery from glucocorticoïd-induced atrophy.

Both physiological and psychological stress cause thymic atrophy via glucocorticoïd (GC)-dependent apoptosis of double-positive (DP) thymocytes. Given the pervasiveness of stress, GC-induced thymic atrophy is arguably the most common type of acquired immunodeficiency. We recently reported that inter...

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Autori principali: Moutih Rafei, Maude Dumont-Lagacé, Alexandre Rouette, Claude Perreault
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2013-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3759406?pdf=render
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