Pseudorabies Virus UL24 Abrogates Tumor Necrosis Factor Alpha-Induced NF-κB Activation by Degrading P65

The transcription factor NF-κB plays a critical role in diverse biological processes. The NF-κB pathway can be activated by incoming pathogens and then stimulates both innate and adaptive immunity. However, many viruses have evolved corresponding strategies to balance NF-κ...

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Main Authors: Tong-Yun Wang, Yue-Lin Yang, Cong Feng, Ming-Xia Sun, Jin-Mei Peng, Zhi-Jun Tian, Yan-Dong Tang, Xue-Hui Cai
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2020-01-01
Series:Viruses
Assuntos:
tnf-α
nf-κb
pseudorabies virus
ul24
p65
Acceso en liña:https://www.mdpi.com/1999-4915/12/1/51
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