In vitro and in vivo characterization of erythrosin B and derivatives against Zika virus

Zika virus (ZIKV) causes significant human diseases without specific therapy. Previously we found erythrosin B, an FDA-approved food additive, inhibited viral NS2B−NS3 interactions, leading to inhibition of ZIKV infection in cell culture. In this study, we performed pharmacokinetic and in vivo studi...

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Detalhes bibliográficos
Main Authors: Zhong Li, Jimin Xu, Yuekun Lang, Xiangmeng Wu, Saiyang Hu, Subodh Kumar Samrat, Anil M. Tharappel, Lili Kuo, David Butler, Yongcheng Song, Qing-Yu Zhang, Jia Zhou, Hongmin Li
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-04-01
Colecção:Acta Pharmaceutica Sinica B
Assuntos:
Flavivirus
Zika virus
Dengue virus
Antiviral
Protease inhibitor
Erythrosin B
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211383521004093
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