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Therapeutics Targeting p53-MDM2 Interaction to Induce Cancer Cell Death

Named as the guardian of the genome, p53 is a tumor suppressor that regulates cell function, often through many different mechanisms such as DNA repair, apoptosis, cell cycle arrest, senescence, metabolism, and autophagy. One of the genes that p53 activates is MDM2, which forms a negative feedback l...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Nayeong Koo, Arun K. Sharma, Satya Narayan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2022-04-01
Sarja:International Journal of Molecular Sciences
Aiheet:
p53
Linkit:https://www.mdpi.com/1422-0067/23/9/5005
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