HOTTIP Predicts Poor Survival in Gastric Cancer Patients and Contributes to Cisplatin Resistance by Sponging miR-216a-5p

Gastric cancer (GC) is a significant public health burden worldwide, and cisplatin resistance is the leading cause for the failure of chemotherapy in this disease. Previous studies have revealed that HOXA transcript at the distal tip (HOTTIP) is involved in the pathology of GC and is associated with...

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Detalhes bibliográficos
Main Authors: Rui Zhao, Xin Zhang, Yanli Zhang, Yaping Zhang, Yongmei Yang, Yue Sun, Xin Zheng, Ailin Qu, Yvette Umwali, Yi Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-05-01
Colecção:Frontiers in Cell and Developmental Biology
Assuntos:
gastric cancer
HOTTIP
miR-216a-5p
autophagy
chemoresistance
Acesso em linha:https://www.frontiersin.org/article/10.3389/fcell.2020.00348/full
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