Sanqi Oral Solution Mitigates Proteinuria in Rat Passive Heymann Nephritis and Blocks Podocyte Apoptosis via Nrf2/HO-1 Pathway

Idiopathic membranous nephropathy (IMN) is the most common pathological type in adult nephrotic syndrome where podocyte apoptosis was found to mediate the development of proteinuria. Sanqi oral solution (SQ), an effective Chinese herbal preparation clinically used in treatment of IMN for decades, pl...

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Main Authors: Xiaowan Wang, Jinchu Liu, Ruimin Tian, Bidan Zheng, Chuang Li, Lihua Huang, Zhisheng Lu, Jing Zhang, Wei Mao, Bo Liu, Kun Bao, Peng Xu
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Assuntos:
Sanqi oral solution
passive Heymann nephritis
podocyte apoptosis
proteinuria
Nrf2/HO-1 signaling pathway
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fphar.2021.727874/full
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