The strange case of AMPK and cancer: Dr Jekyll or Mr Hyde?†

The AMP-activated protein kinase (AMPK) acts as a cellular energy sensor. Once switched on by increases in cellular AMP : ATP ratios, it acts to restore energy homeostasis by switching on catabolic pathways while switching off cell growth and proliferation. The canonical AMP-dependent mechanism of a...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Diana Vara-Ciruelos, Fiona M. Russell, D. Grahame Hardie
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2019-07-01
Edice:Open Biology
Témata:
ampk
cancer
lkb1
metabolism
tumour suppressors
tumour promoters
On-line přístup:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.190099
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky