Comprehensive routine diagnostic screening to identify predictive mutations, gene amplifications, and microsatellite instability in FFPE tumor material

Abstract Background Sensitive and reliable molecular diagnostics is needed to guide therapeutic decisions for cancer patients. Although less material becomes available for testing, genetic markers are rapidly expanding. Simultaneous detection of predictive markers, including mutations, gene amplific...

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書誌詳細
主要な著者: Elisabeth M. P. Steeghs, Leonie I. Kroeze, Bastiaan B. J. Tops, Leon C. van Kempen, Arja ter Elst, Annemiek W. M. Kastner-van Raaij, Sandra J. B. Hendriks-Cornelissen, Mandy J. W. Hermsen, Erik A. M. Jansen, Petra M. Nederlof, Ed Schuuring, Marjolijn J. L. Ligtenberg, Astrid Eijkelenboom
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2020-04-01
シリーズ:BMC Cancer
主題:
Predictive analysis
Next-generation sequencing
Mutation
Gene amplification
Microsatellite instability
FFPE
オンライン･アクセス:http://link.springer.com/article/10.1186/s12885-020-06785-6
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