Low-Luminance Blue Light-Enhanced Phototoxicity in A2E-Laden RPE Cell Cultures and Rats

N-retinylidene-N-retinylethanolamine (A2E) and other bisretinoids are components of lipofuscin and accumulate in retinal pigment epithelial (RPE) cells—these adducts are recognized in the pathogenesis of retinal degeneration. Further, blue light-emitting diode (LED) light (BLL)-induced ret...

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Autori principali: Cheng-Hui Lin, Man-Ru Wu, Wei-Jan Huang, Diana Shu-Lian Chow, George Hsiao, Yu-Wen Cheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2019-04-01
Serie:International Journal of Molecular Sciences
Soggetti:
blue light
N-retinylidene-N-retinylethanolamine (A2E)
retinal pigment epithelial cells (RPE)
retinal damage
Accesso online:https://www.mdpi.com/1422-0067/20/7/1799
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