COX-2 Gene Promoter Methylation in Patients Infected with

Cyclooxygenase (COX) plays a critical role in peptic ulcer development. COX-2 contains CpG islands in promoter area, which suggests possible epigenetic mechanisms of gene silencing. We evaluated COX-2 gene promoter methylation levels in the gastric mucosa of patients with various gastric diseases. D...

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Bibliographic Details
Main Authors: Yosuke Michikawa, Hiroshi Yasuda, Yoshiyuki Watanabe, Ritsuko Oikawa, Yoshichika Ohishi, Tadateru Maehata, Fumio Itoh
Format: Artigo
Language:Inglês
Published: SAGE Publishing 2013-01-01
Series:Clinical Medicine Insights: Gastroenterology
Online Access:https://doi.org/10.4137/CGast.S11917
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