Inhibition of LINE-1 Retrotransposition by Capsaicin

Long interspersed nuclear element 1 (LINE-1 or L1) is a non-long terminal repeat (LTR) retrotransposon that constitutes approximately 17% of the human genome. Since approximately 100 copies are still competent for retrotransposition to other genomic loci, dysregulated retrotransposition of L1 is con...

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Detalhes bibliográficos
Main Authors: Yuki Nishikawa, Ryota Nakayama, Shunsuke Obika, Eriko Ohsaki, Keiji Ueda, Tomoyuki Honda
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2018-10-01
Colecção:International Journal of Molecular Sciences
Assuntos:
anti-cancer
capsaicin
inhibitor
LINE-1
L1
phytochemicals
retrotransposition
reverse transcriptase
Acesso em linha:http://www.mdpi.com/1422-0067/19/10/3243
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