Systems Biology Approaches Reveal Potential Phenotype-Modifier Genes in Neurofibromatosis Type 1

Neurofibromatosis type (NF1) is a syndrome characterized by varied symptoms, ranging from mild to more aggressive phenotypes. The variation is not explained only by genetic and epigenetic changes in the <i>NF1</i> gene and the concept of phenotype-modifier genes in extensively discussed...

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Main Authors: Thayne Woycinck Kowalski, Larissa Brussa Reis, Tiago Finger Andreis, Patricia Ashton-Prolla, Clévia Rosset
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-08-01
Colecção:Cancers
Assuntos:
neurofibromatosis type 1
phenotype-modifier genes
systems biology
Acesso em linha:https://www.mdpi.com/2072-6694/12/9/2416
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