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An adjuvanted zoster vaccine elicits potent cellular immune responses in mice without QS21

Abstract Herpes zoster (HZ) is caused by reactivation of latent varicella-zoster virus (VZV) when VZV-specific cellular immunity is insufficient to control reactivation. Currently, Shingrix, which contains the VZV gE protein and GSK’s AS01B adjuvant composed of liposomes formulated with cholesterol,...

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Detalhes bibliográficos
Main Authors: Hyo Jung Nam, Sung Jun Hong, Ara Lee, Jiyeon Kim, Sangho Lee, Corey Casper, Darrick Carter, Steven G. Reed, George Simeon, Eui-Cheol Shin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2022-04-01
Colecção:npj Vaccines
Acesso em linha:https://doi.org/10.1038/s41541-022-00467-z
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