A Kinase Anchor Protein 4 Is Vulnerable to Oxidative Adduction in Male Germ Cells

Oxidative stress is a leading causative agent in the defective sperm function associated with male infertility. Such stress commonly manifests via the accumulation of pathological levels of the electrophilic aldehyde, 4-hydroxynonenal (4HNE), generated as a result of lipid peroxidation. This highly...

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Autores principales: Brett Nixon, Ilana R. Bernstein, Shenae L. Cafe, Maryse Delehedde, Nicolas Sergeant, Amanda L. Anderson, Natalie A. Trigg, Andrew L. Eamens, Tessa Lord, Matthew D. Dun, Geoffry N. De Iuliis, Elizabeth G. Bromfield
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019-12-01
Colección:Frontiers in Cell and Developmental Biology
Materias:
4-hydroxynonenal
A-kinase anchor protein 4
male germ cells
oxidative stress
spermatozoa
sperm capacitation
Acceso en línea:https://www.frontiersin.org/article/10.3389/fcell.2019.00319/full
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