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The Mechanism of Ferroptosis and Applications in Tumor Treatment

Iron-dependent ferroptosis is a new form of cell death in recent years, which is driven by lipid peroxidation. The lethal lipid accumulation caused by glutathione depletion or inactivation of glutathione peroxidase 4 (GPX4) is characteristic of the ferroptosis process. In recent years, with the in-d...

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Hlavní autoři: Xinyue Lin, Jieyi Ping, Yi Wen, Yan Wu
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020-07-01
Edice:Frontiers in Pharmacology
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On-line přístup:https://www.frontiersin.org/article/10.3389/fphar.2020.01061/full
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