RNA-seq analysis of extracellular vesicles from hyperphosphatemia-stimulated endothelial cells provides insight into the mechanism underlying vascular calcification

Abstract Background Hyperphosphatemia (HP) is associated with vascular calcification (VC) in chronic kidney disease (CKD). However, relationship between HP-induced-endothelial extracellular vesicles (HP-EC-EVs) and VC is unclear, and miR expression in HP-EC-EVs has not been determined. Methods We is...

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Hlavní autoři: Zhong Peng, Yingjie Duan, Shuzhu Zhong, Juan Chen, Jianlong Li, Zhangxiu He
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2022-05-01
Edice:BMC Nephrology
Témata:
Hyperphosphatemia
Extracellular vesicles (EVs)
Vascular calcification
High-throughput sequencing (HTS)
On-line přístup:https://doi.org/10.1186/s12882-022-02823-6
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