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Does the Inhibitory Action of Asymmetric Dimethylarginine (ADMA) on the Endothelial Nitric Oxide Synthase Activity Explain Its Importance in the Cardiovascular System? The ADMA Paradox

Asymmetric dimethylarginine (ADMA, NG, NG-dimethyl-L-arginine) is endogenously produced by asymmetric dimethylation of the guanidine group of L-arginine residues. ADMA is generally considered a powerful cardiovascular risk factor, an Übermarker, due to its inhibitory action on the activity of nitric...

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Detalhes bibliográficos
Autor principal: Dimitrios Tsikas
Formato: Artigo
Idioma:Inglês
Publicado em: Biogenic Press 2017-07-01
Colecção:Journal of Controversies in Biomedical Research
Assuntos:
Acesso em linha:https://jcbmr.com/index.php/jcbmr/article/view/22
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