Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival.

Tobacco smoking is responsible for over 90% of lung cancer cases, and yet the precise molecular alterations induced by smoking in lung that develop into cancer and impact survival have remained obscure.We performed gene expression analysis using HG-U133A Affymetrix chips on 135 fresh frozen tissue s...

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Autori principali: Maria Teresa Landi, Tatiana Dracheva, Melissa Rotunno, Jonine D Figueroa, Huaitian Liu, Abhijit Dasgupta, Felecia E Mann, Junya Fukuoka, Megan Hames, Andrew W Bergen, Sharon E Murphy, Ping Yang, Angela C Pesatori, Dario Consonni, Pier Alberto Bertazzi, Sholom Wacholder, Joanna H Shih, Neil E Caporaso, Jin Jen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2008-02-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC2249927?pdf=render
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