Synthesis and Anti-Trypanosoma cruzi Activity of Diaryldiazepines

Chagas disease is a so-called “neglected disease” and endemic to Latin America. Nifurtimox and benznidazole are drugs that have considerable efficacy in the treatment of the acute phase of the disease but cause many significant side effects. Furthermore, in the Chronic Phase its efficiency is reduc...

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Bibliographic Details
Main Authors: Júlio César L. Menezes, Luana Beatriz A. Vaz, Paula Melo de Abreu Vieira, Kátia da Silva Fonseca, Cláudia Martins Carneiro, Jason G. Taylor
Format: Artigo
Language:Inglês
Published: MDPI AG 2014-12-01
Series:Molecules
Subjects:
diaryldiazepines
Trypanosoma cruzi
Chagas disease
epimastigote
Online Access:http://www.mdpi.com/1420-3049/20/1/43
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