The oncogenic potential of a mutant TP53 gene explored in two spontaneous lung cancer mice models

Abstract Background Lung cancer is the number one cancer killer worldwide. A major drawback in the lung cancer treatment field is the lack of realistic mouse models that replicate the complexity of human malignancy and immune contexture within the tumor microenvironment. Such models are urgently nee...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Julian Ramelow, Christopher D. Brooks, Li Gao, Abeer A. Almiman, Terence M. Williams, Miguel A. Villalona-Calero, Wenrui Duan
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2020-08-01
Edice:BMC Cancer
Témata:
Lung cancer
Mouse model
TP53 mutation
Immunotherapy
On-line přístup:http://link.springer.com/article/10.1186/s12885-020-07212-6
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky