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The oncogenic potential of a mutant TP53 gene explored in two spontaneous lung cancer mice models

Abstract Background Lung cancer is the number one cancer killer worldwide. A major drawback in the lung cancer treatment field is the lack of realistic mouse models that replicate the complexity of human malignancy and immune contexture within the tumor microenvironment. Such models are urgently nee...

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Main Authors: Julian Ramelow, Christopher D. Brooks, Li Gao, Abeer A. Almiman, Terence M. Williams, Miguel A. Villalona-Calero, Wenrui Duan
格式: Artigo
語言:Inglês
出版: BMC 2020-08-01
叢編:BMC Cancer
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在線閱讀:http://link.springer.com/article/10.1186/s12885-020-07212-6
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