Evidence of Inbreeding in Hodgkin Lymphoma.

Genome-wide association studies (GWASs) have identified several, mainly co-dominantly acting, single-nucleotide polymorphisms (SNPs) associated with Hodgkin lymphoma (HL). We searched for recessively acting disease loci by performing an analysis of runs of homozygosity (ROH) based on windows of homo...

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Главные авторы: Hauke Thomsen, Miguel Inacio da Silva Filho, Michael Fuchs, Sabine Ponader, Elke Pogge von Strandmann, Lewin Eisele, Stefan Herms, Per Hoffmann, Andreas Engert, Kari Hemminki, Asta Försti
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2016-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC4849743?pdf=render
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