Single nucleotide-level mapping of DNA double-strand breaks in human HEK293T cells

Constitutional biological processes involve the generation of DNA double-strand breaks (DSBs). The production of such breaks and their subsequent resolution are also highly relevant to neurodegenerative diseases and cancer, in which extensive DNA fragmentation has been described Stephens et al. (201...

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Main Authors: Bernard J. Pope, Khalid Mahmood, Chol-hee Jung, Peter Georgeson, Daniel J. Park
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017-03-01
Serier:Genomics Data
Fag:
Double-strand breaks
Fragile sites
Human genome
Forum domains
HEK293T
Online adgang:http://www.sciencedirect.com/science/article/pii/S2213596016301428
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