BRIDGE −1 TRIAL: BReak Interval Delayed surgery for Gastrointestinal Extraperitoneal rectal cancer, a multicentric phase III randomized trial

Design: Neoadjuvant chemoradiotherapy (nCRT) followed by surgery is the standard of care for locally advanced rectal cancer (LARC).Several studies have shown a correlation between a longer interval between the end of nCRT and surgery (surgical interval - SI) and an increased pathological complete re...

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Main Authors: Giuditta Chiloiro, Elisa Meldolesi, Barbara Corvari, Angela Romano, Brunella Barbaro, Claudio Coco, Antonio Crucitti, Domenico Genovesi, Marco Lupattelli, Giovanna Mantello, Roberta Menghi, Mattia Falchetto Osti, Roberto Persiani, Lucio Petruzziello, Riccardo Ricci, Luigi Sofo, Chiara Valentini, Antonino De Paoli, Vincenzo Valentini, Maria Antonietta Gambacorta
Format: Artigo
Language:Inglês
Published: Elsevier 2022-05-01
Series:Clinical and Translational Radiation Oncology
Subjects:
Rectal cancer
Surgical Interval
Neoadjuvant chemoradiotherapy
Personalized treatment
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630822000155
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