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Common biochemical properties of metabolic genes recurrently dysregulated in tumors
Abstract Background Tumor initiation and progression are associated with numerous metabolic alterations. However, the biochemical drivers and constraints that contribute to metabolic gene dysregulation are unclear. Methods Here, we present MetOncoFit, a computational model that integrates 142 metabo...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BMC
2020-05-01
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Colecção: | Cancer & Metabolism |
Assuntos: | |
Acesso em linha: | http://link.springer.com/article/10.1186/s40170-020-0211-1 |
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