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Common biochemical properties of metabolic genes recurrently dysregulated in tumors

Abstract Background Tumor initiation and progression are associated with numerous metabolic alterations. However, the biochemical drivers and constraints that contribute to metabolic gene dysregulation are unclear. Methods Here, we present MetOncoFit, a computational model that integrates 142 metabo...

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Main Authors: Krishnadev Oruganty, Scott Edward Campit, Sainath Mamde, Costas A. Lyssiotis, Sriram Chandrasekaran
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-05-01
Colecção:Cancer & Metabolism
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Acesso em linha:http://link.springer.com/article/10.1186/s40170-020-0211-1
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