Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults.

Studying ethnically diverse groups is important for furthering our understanding of biological mechanisms of disease that may vary across human populations. The ε4 allele of apolipoprotein E (APOE ε4) is a well-established risk factor for Alzheimer's disease (AD), and may confer anatomic and fu...

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Detalhes bibliográficos
Main Authors: Jennifer S Yokoyama, Allen K L Lee, Leonel T Takada, Edgar Busovaca, Luke W Bonham, Steven Z Chao, Marian Tse, Jing He, Christopher G Schwarz, Owen T Carmichael, Brandy R Matthews, Anna Karydas, Michael W Weiner, Giovanni Coppola, Charles S DeCarli, Bruce L Miller, Howard J Rosen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4349764?pdf=render
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