Zinc fingers function cooperatively with KRAB domain for nuclear localization of KRAB-containing zinc finger proteins.

Multiple nuclear localization domains have been identified in nuclear proteins, and they finely control nuclear import and functions of those proteins. ZNF268 is a typical KRAB-containing zinc finger protein (KRAB-ZFP), and previous studies have shown that the KRAB domain reinforces nuclear localiza...

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Main Authors: Wei Wang, Jinyang Cai, Yi Lin, Zikou Liu, Qihao Ren, Li Hu, Zan Huang, Mingxiong Guo, Wenxin Li
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2014-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC3960175?pdf=render
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