From Belly to Brain: Targeting the Ghrelin Receptor in Appetite and Food Intake Regulation

Ghrelin is the only known peripherally-derived orexigenic hormone, increasing appetite and subsequent food intake. The ghrelinergic system has therefore received considerable attention as a therapeutic target to reduce appetite in obesity as well as to stimulate food intake in conditions of anorexia...

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Bibliografische gegevens
Hoofdauteurs: Ken Howick, Brendan T. Griffin, John F. Cryan, Harriët Schellekens
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2017-01-01
Reeks:International Journal of Molecular Sciences
Onderwerpen:
ghrelin
desacyl-ghrelin
appetite
GHSR-1a
obesity
cachexia
food reward
mesolimbic reward circuitry
blood brain barrier
Online toegang:http://www.mdpi.com/1422-0067/18/2/273
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