NUP133 Controls Nuclear Pore Assembly, Transcriptome Composition, and Cytoskeleton Regulation in Podocytes

Steroid-resistant nephrotic syndrome (SRNS) frequently leads to end-stage renal disease, ultimately requiring kidney replacement therapies. SRNS is often caused by hereditary monogenic mutations, specifically affecting specialized epithelial cells (podocytes) of the glomerular filtration barrier. Mu...

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Détails bibliographiques
Auteurs principaux: Manuel Rogg, Jasmin I. Maier, Markus Ehle, Alena Sammarco, Oliver Schilling, Martin Werner, Christoph Schell
Format: Artigo
Langue:Inglês
Publié: MDPI AG 2022-04-01
Collection:Cells
Sujets:
NUP133
nuclear pore complex
nucleoporin
podocyte
SRNS
podocytopathy
Accès en ligne:https://www.mdpi.com/2073-4409/11/8/1259
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