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Differential requirement for cathepsin D for processing of the full length and C-terminal fragment of the malaria antigen MSP1.

Merozoite Surface Protein 1 is expressed on the surface of malaria merozoites and is important for invasion of the malaria parasite into erythrocytes. MSP1-specific CD4 T cell responses and antibody can confer protective immunity in experimental models of malaria. In this study we explore the contri...

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Main Authors: Calogero Tulone, Anne-Marit Sponaas, Eun-Ang Raiber, Alethea B Tabor, Jean Langhorne, Benny M Chain
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2011-01-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC3203867?pdf=render
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