Reactive oxygen species are required for maintenance and differentiation of primary lung fibroblasts in idiopathic pulmonary fibrosis.

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal illness whose pathogenesis remains poorly understood. Recent evidence suggests oxidative stress as a key player in the establishment/progression of lung fibrosis in animal models and possibly in human IPF. The aim of the pres...

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Main Authors: Marialuisa Bocchino, Savina Agnese, Evelina Fagone, Silvia Svegliati, Domenico Grieco, Carlo Vancheri, Armando Gabrielli, Alessandro Sanduzzi, Enrico V Avvedimento
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2010-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC2982828?pdf=render
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