Insertions and Duplications in the Polyproline Region of the Hepatitis E Virus

Recombinant strains of hepatitis E virus (HEV) with insertions of human genomic fragments or HEV sequence duplications in the sequence encoding the polyproline region (PPR) were previously described in chronically infected patients. Such genomic rearrangements confer a replicative advantage in vitro...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sébastien Lhomme, Florence Nicot, Nicolas Jeanne, Chloé Dimeglio, Alain Roulet, Caroline Lefebvre, Romain Carcenac, Maxime Manno, Martine Dubois, Jean-Marie Peron, Laurent Alric, Nassim Kamar, Florence Abravanel, Jacques Izopet
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020-01-01
Collection:Frontiers in Microbiology
Sujets:
hepatitis E virus
polyproline region
genomic rearrangement
virus-host recombinant variants
virus-virus recombinant variants
Accès en ligne:https://www.frontiersin.org/article/10.3389/fmicb.2020.00001/full
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires