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Predicting novel drugs for SARS-CoV-2 using machine learning from a >10 million chemical space

There is an urgent need for the identification of effective therapeutics for COVID-19 and we have developed a machine learning drug discovery pipeline to identify several drug candidates. First, we collect assay data for 65 target human proteins known to interact with the SARS-CoV-2 proteins, includ...

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Bibliografiske detaljer
Main Authors: Joel Kowalewski, Anandasankar Ray
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020-08-01
Serier:Heliyon
Fag:
Online adgang:http://www.sciencedirect.com/science/article/pii/S2405844020314833
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