Comprehensive Analysis of the Structure and Function of Peptide:N-Glycanase 1 and Relationship with Congenital Disorder of Deglycosylation

The cytosolic PNGase (peptide:N-glycanase), also known as peptide-N4-(N-acetyl-β-glucosaminyl)-asparagine amidase, is a well-conserved deglycosylation enzyme (EC 3.5.1.52) which catalyzes the non-lysosomal hydrolysis of an N(4)-(acetyl-β-<span style="font-variant: small-caps;">d</...

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Main Authors: Xiangguang Miao, Jin Wu, Hongping Chen, Guanting Lu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-04-01
Colecção:Nutrients
Assuntos:
N-glycosylation
NGLY1
ER associated degradation process
congenital disorder of deglycosylation
NFE2L1
Acesso em linha:https://www.mdpi.com/2072-6643/14/9/1690
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