The effects of antibiotic cycling and mixing on acquisition of antibiotic resistant bacteria in the ICU: A post-hoc individual patient analysis of a prospective cluster-randomized crossover study

<h4>Background</h4> Repeated rotation of empiric antibiotic treatment strategies is hypothesized to reduce antibiotic resistance. Clinical rotation studies failed to change unit-wide prevalence of antibiotic resistant bacteria (ARB) carriage, including an international cluster-randomized...

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Main Authors: Pleun J. van Duijn, Walter Verbrugghe, Philippe G. Jorens, Fabian Spöhr, Dirk Schedler, Maria Deja, Andreas Rothbart, Djillali Annane, Christine Lawrence, Matjaz Jereb, Katja Seme, Franc Šifrer, Viktorija Tomič, Francisco Estevez, Jandira Carneiro, Stephan Harbarth, Marc J. M. Bonten
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2022-01-01
Colecção:PLoS ONE
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064081/?tool=EBI
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