Human tear peptide/protein profiling study of ocular surface diseases by SPE-MALDI-TOF mass spectrometry analyses

The goal of this study was to investigate differences in tear peptidome/proteome profiles of aqueous-deficient dry eye, Meibomian gland dysfunction and control individuals. Tears from 93 individuals were collected by capillary and subjected to solid-phase extraction followed by MALDI-TOF for profili...

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Detalhes bibliográficos
Main Authors: Nerea González, Ibon Iloro, Javier Soria, Juan A. Duran, Alaitz Santamaría, Felix Elortza, Tatiana Suárez
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014-06-01
Colecção:EuPA Open Proteomics
Assuntos:
Dry eye
Meibomian gland dysfunction
Tears
MALDI-TOF
Profiling
Warping
Peptidomics
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S221296851400021X
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