Cholesterol Homeostasis Modulates Platinum Sensitivity in Human Ovarian Cancer

Despite initial chemotherapy response, ovarian cancer is the deadliest gynecologic cancer, due to frequent relapse and onset of drug resistance. To date, there is no affordable diagnostic/prognostic biomarker for early detection of the disease. However, it has been recently shown that high grade ser...

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Detalhes bibliográficos
Main Authors: Daniela Criscuolo, Rosario Avolio, Giovanni Calice, Chiara Laezza, Simona Paladino, Giovanna Navarra, Francesca Maddalena, Fabiana Crispo, Cristina Pagano, Maurizio Bifulco, Matteo Landriscina, Danilo Swann Matassa, Franca Esposito
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-03-01
Colecção:Cells
Assuntos:
ovarian cancer
TRAP1
cholesterol homeostasis
platinum resistance
Acesso em linha:https://www.mdpi.com/2073-4409/9/4/828
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https://www.mdpi.com/2073-4409/9/4/828

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