Chargement en cours...
Inhibition of Ras GTPases prevents Collagen‐Induced Arthritis by Reducing the Generation of Pathogenic CD4+ T Cells and the Hyposialylation of Autoantibodies
Objective RasGTPases are master regulators of multiple intracellular signaling cascades. Perturbation of this pathway has been implicated in the pathogenesis of rheumatoid arthritis (RA). In this study we aimed to define the therapeutic potential of a novel RasGTPases inhibitor, farnesylthiosalicyla...
Enregistré dans:
| Auteurs principaux: | , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Wiley
2020-09-01
|
| Collection: | ACR Open Rheumatology |
| Accès en ligne: | https://doi.org/10.1002/acr2.11169 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|