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eNOS-dependent antisenscence effect of a calcium channel blocker in human endothelial cells.

Senescence of vascular endothelial cells is an important contributor to the pathogenesis of age-associated vascular disorders such as atherosclerosis. We investigated the effects of antihypertensive agents on high glucose-induced cellular senescence in human umbilical venous endothelial cells (HUVEC...

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Bibliografiske detaljer
Main Authors: Toshio Hayashi, Tomoe Yamaguchi, Yasufumi Sakakibara, Kumiko Taguchi, Morihiko Maeda, Masafumi Kuzuya, Yuichi Hattori
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2014-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC3919771?pdf=render
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