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Homotypic and Heterotypic Activation of the Notch Pathway in Multiple Myeloma–Enhanced Angiogenesis: A Novel Therapeutic Target?
Interactions of multiple myeloma (MM) cells with endothelial cells (ECs) enhance angiogenesis and MM progression. Here, we investigated the role of Notch signaling in the cross talk between ECs and MM cells enabling angiogenesis. MMECs showed higher expression of Jagged1/2 ligands, of activated Notc...
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主要な著者: | , , , , , , , , , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Elsevier
2019-01-01
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シリーズ: | Neoplasia: An International Journal for Oncology Research |
オンライン・アクセス: | http://www.sciencedirect.com/science/article/pii/S1476558618305025 |
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