SARM1 Depletion Slows Axon Degeneration in a CNS Model of Neurotropic Viral Infection

Zika virus (ZIKV) is a neurotropic flavivirus recently linked to congenital ZIKV syndrome in children and encephalitis and Guillain-Barré syndrome in adults. Neurotropic viruses often use axons to traffic to neuronal or glial cell somas where they either remain latent or replicate and proceed to inf...

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Autores principales: Colin L. Crawford, Christina Antoniou, Lina Komarek, Verena Schultz, Claire L. Donald, Paul Montague, Susan C. Barnett, Christopher Linington, Hugh J. Willison, Alain Kohl, Michael P. Coleman, Julia M. Edgar
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2022-04-01
Colección:Frontiers in Molecular Neuroscience
Materias:
Zika virus
neurofilament
tubulin (microtubules)
glia
nicotinamide adenine dinucleotide
Acceso en línea:https://www.frontiersin.org/articles/10.3389/fnmol.2022.860410/full
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