Herpes Simplex Virus 1 UL2 Inhibits the TNF-α–Mediated NF-κB Activity by Interacting With p65/p50

Herpes simplex virus 1 (HSV-1) is a large double-stranded DNA virus that encodes at least 80 viral proteins, many of which are involved in the virus–host interaction and are beneficial to the viral survival and reproduction. However, the biological functions of some HSV-1–encoded proteins are not fu...

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Bibliographic Details
Main Authors: Mingsheng Cai, Zongmin Liao, Xingmei Zou, Zuo Xu, Yuanfang Wang, Tong Li, Yiwen Li, Xiaowen Ou, Yangxi Deng, Yingjie Guo, Tao Peng, Meili Li
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
innate immunity
HSV-1
UL2
NF-κB
IL-8
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00549/full
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