Genetic and Clinical Factors Associated with Olokizumab Treatment in Russian Patients with Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease and its treatment is an urgent problem of rheumatology. Olokizumab (OKZ) is a new humanized monoclonal antibody targeting IL-6 and is one of the few promising drugs for RA therapy. One-hundred-and-twenty-five DNA samples from Russi...

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Detalhes bibliográficos
Main Authors: Dmitry S. Mikhaylenko, Ekaterina B. Kuznetsova, Viktoria V. Musatova, Irina V. Bure, Tatiana A. Deryagina, Ekaterina A. Alekseeva, Vadim V. Tarasov, Andrey A. Zamyatnin, Marina V. Nemtsova
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-04-01
Colecção:Journal of Personalized Medicine
Assuntos:
rheumatoid arthritis
olokizumab
genetic predisposition
genotyping
NGS
response to therapy
Acesso em linha:https://www.mdpi.com/2075-4426/12/4/641
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