The Type 2 Diabetes Susceptibility PROX1 Gene Variants Are Associated with Postprandial Plasma Metabolites Profile in Non-Diabetic Men

The prospero homeobox 1 (PROX1) gene may show pleiotropic effects on metabolism. We evaluated postprandial metabolic alterations dependently on the rs340874 genotypes, and 28 non-diabetic men were divided into two groups: high-risk (HR)-genotype (CC-genotype carriers, <i>n</i> = 12, 35.3...

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Hlavní autoři: Edyta Adamska-Patruno, Joanna Godzien, Michal Ciborowski, Paulina Samczuk, Witold Bauer, Katarzyna Siewko, Maria Gorska, Coral Barbas, Adam Kretowski
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2019-04-01
Edice:Nutrients
Témata:
nutrigenetics
nutrimetabolomics
high-carbohydrate meal
normo-carbohydrate meal
postprandial metabolic fingerprinting
ultra-high performance liquid chromatography
PROX1 gene
type 2 diabetes mellitus risk
On-line přístup:https://www.mdpi.com/2072-6643/11/4/882
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