Chikusetsu Saponin V Attenuates MPP+-Induced Neurotoxicity in SH-SY5Y Cells via Regulation of Sirt1/Mn-SOD and GRP78/Caspase-12 Pathways

Studies have shown that saponins from Panax japonicus (SPJ) possess neuroprotective effects. However, whether Chikusetsu saponin V (CsV), the most abundant member of SPJ, can exert neuroprotective effects against 1-methyl-4-phenylpyridinium ion (MPP+)-induced cytotoxicity is not known. In this study...

Full description

Saved in:
Bibliographic Details
Main Authors: Ding Yuan, Jing-Zhi Wan, Li-Li Deng, Chang-Cheng Zhang, Yao-Yan Dun, Yan-Wen Dai, Zhi-Yong Zhou, Chao-Qi Liu, Ting Wang
Format: Artigo
Language:Inglês
Published: MDPI AG 2014-07-01
Series:International Journal of Molecular Sciences
Subjects:
Chikusetsu saponin V
MPP+
Sirt1
GRP78
Online Access:http://www.mdpi.com/1422-0067/15/8/13209
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items