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Parallel roles of transcription factors dFOXO and FER2 in the development and maintenance of dopaminergic neurons.

Forkhead box (FOXO) proteins are evolutionarily conserved, stress-responsive transcription factors (TFs) that can promote or counteract cell death. Mutations in FOXO genes are implicated in numerous pathologies, including age-dependent neurodegenerative disorders, such as Parkinson's disease (P...

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Main Authors: Damla Tas, Luca Stickley, Federico Miozzo, Rafael Koch, Nicolas Loncle, Virginie Sabado, Bettina Gnägi, Emi Nagoshi
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2018-03-01
叢編:PLoS Genetics
在線閱讀:http://europepmc.org/articles/PMC5864087?pdf=render
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