In Vitro Regeneration of Patient-specific Ear-shaped Cartilage and Its First Clinical Application for Auricular Reconstruction

Microtia is a congenital external ear malformation that can seriously influence the psychological and physiological well-being of affected children. The successful regeneration of human ear-shaped cartilage using a tissue engineering approach in a nude mouse represents a promising approach for auric...

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Bibliographic Details
Main Authors: Guangdong Zhou, Haiyue Jiang, Zongqi Yin, Yu Liu, Qingguo Zhang, Chen Zhang, Bo Pan, Jiayu Zhou, Xu Zhou, Hengyun Sun, Dan Li, Aijuan He, Zhiyong Zhang, Wenjie Zhang, Wei Liu, Yilin Cao
Format: Artigo
Language:Inglês
Published: Elsevier 2018-02-01
Series:EBioMedicine
Subjects:
Microtia chondrocytes
Human ear-shaped cartilage
In vitro engineering
3D printing
Polycaprolactone (PCL)
Clinical trial
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418300161
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