Revisiting the Growth Modulon of Corynebacterium glutamicum Under Glucose Limited Chemostat Conditions

Increasing the growth rate of the industrial host Corynebacterium glutamicum is a promising target to rise productivities of growth coupled product formation. As a prerequisite, detailed knowledge about the tight regulation network is necessary for identifying promising metabolic engineering goals....

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Main Authors: Michaela Graf, Thorsten Haas, Attila Teleki, André Feith, Martin Cerff, Wolfgang Wiechert, Katharina Nöh, Tobias Busche, Jörn Kalinowski, Ralf Takors
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-10-01
Colecção:Frontiers in Bioengineering and Biotechnology
Assuntos:
Corynebacterium glutamicum
growth rate
metabolome
transcriptome
continuous bioprocess
stationary flux analysis
Acesso em linha:https://www.frontiersin.org/article/10.3389/fbioe.2020.584614/full
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