Tumor suppressor WWOX and p53 alterations and drug resistance in glioblastomas

Tumor suppressor p53 are frequently mutated in glioblastomas (GBMs) and appears to contribute, in part, to resistance to temozolomide and therapeutic drugs. WW domain-containing oxidoreductase WWOX (FOR or WOX1) is a proapoptotic protein and is considered as a tumor suppressor. Loss of WWOX gene exp...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Ming-Fu eChiang, Pei-Yi eChou, Wan-Jen eWang, Chun-I eSze, Nan-Shan eChang
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2013-03-01
Col·lecció:Frontiers in Oncology
Matèries:
p53
tumor suppressor
Glioblastoma Multiforme
WWOX
temozolomide resistance
Accés en línia:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00043/full
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars